![]() As a result, side effects such as indigestion, nausea, and ulcers are not uncommon. However, this same mechanism can reduce the protective benefits that COX has on the lining of the stomach. This expanded action contributes, in part, to the drugs' analgesic, anti-inflammatory, and antipyretic effects. However, unlike acetaminophen, NSAIDs selectively inhibit COX-1 and COX-2 not just in the central nervous system but in other parts of the body also. As with acetaminophen, NSAIDs are available in many different formulations including pills, syrups, and patches.
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